Liana Bauer, KIT

August 21, 2025

Until now, the early phase of drug discovery for the development of new therapeutics has been both cost- and time-intensive. Researchers at KIT (Karlsruhe Institute of Technology) have now developed a platform on which extremely miniaturized nanodroplets with a volume of only 200 nanoliters per droplet – comparable to a grain of sand – and containing only 300 cells per test can be arranged. This platform enables the researchers to synthesize, characterize, and test thousands of therapeutic agents on the same chip, saving time and resources. The researchers report on their findings in the journal “Angewandte Chemie” (DOI: 10.1002/anie.202507586)

Kajum Safiullin, KIT

August 21, 2025

[jho] Nuclear magnetic resonance forms the basis of both nuclear magnetic resonance spectroscopy (NMR spectroscopy), which is used to analyze solids or organic molecules in liquids, and magnetic resonance imaging for medical diagnostic purposes. Researchers at Karlsruhe Institute of Technology (KIT) and Leipzig University have now, for the first time, experimentally demonstrated that extended measurement techniques are possible (Phys. Rev. B 112, L060302 – DOI: https://doi.org/10.1103/h2sn-wvzm).

Although additional resonanceshad been theoretically predicted, they had not been observed due to their minimal effects. “We used a calcium fluoride single crystal as the sample material, in which fluorine atoms are arranged in a cubic lattice,” explains Dr. Benno Meier from Institute of Biological Interfaces 4 at KIT and head of a Helmholtz Young Investigator Group. “The key was that we repeatedly changed the strength of the magnetic field abruptly. This allowed us to discover resonance frequencies far from the Larmor frequency. The experimental results align excellently with theoretical predictions.”

Transferring these findings to electron spin resonance (ESR) spectroscopy, which is used in biophysics and materials science, also promises new applications.

Lena Pilz, KIT

June 06, 2025

Metal-organic frameworks (MOFs) are characterized by high porosity and structural versatility. They have enormous potential, for example for applications in electronics. However, their low electrical conductivity has so far greatly restricted their adoption. Using AI and robot-assisted synthesis in a self-driving laboratory, researchers from Karlsruhe Institute of Technology (KIT), together with colleagues in Germany and Brazil, have now succeeded in producing an MOF thin film that conducts electricity like metals. This opens up new possibilities in electronics and energy storage – from sensors and quantum materials to functional materials. The team reports in the Materials Horizons journal. (DOI: 10.1039/d5mh00813a)

Maryna Leonidivna Meretska, KIT

March 03, 2025

Conventional curved lenses, which direct light by refraction in glass or plastic, are often bulky and heavy, offering only limited control of light waves. Metasurfaces, in contrast, are flat and consist of an array of tiny structures known as meta-atoms. Meta-atoms influence light at a subwavelength scale and thus allow for highly precise control of the phase, amplitude, and polarization of light. “Using metasurfaces, we can influence the temporal shift, intensity, and direction of oscillation of light waves in a targeted way,” says Dr. Maryna Leonidivna Meretska, Group Leader at KIT’s Institute of Nanotechnology. “Thanks to its multiplex control capabilities, i.e. the simultaneous and targeted influencing of various parameters, a single metasurface can replace multiple optical components. Thus, the size of the optical system can be reduced without affecting its performance.” Production will also be simpler, “Metasurfaces can be manufactured using advanced lithography and etching technologies from the semiconductor industry, making scalable production is possible,” says Meretska.

Read more about optical Metasurfaces

KIT

February 05, 2025

Researchers at the Karlsruhe Institute of Technology (KIT) have synthesized a Bi5--ring, a molecule with five bismuth atoms, and stabilized it in a metal complex. Their discovery fills a gap in chemical knowledge and enables future applications in materials research, catalysis, and electronics. Their findings have been published in Nature Chemistry. (DOI: 10.1038/s41557-024-01713-8)

Marco Schilling

January 27, 2025

Prof. Dr. Stefanie Dehnen und Prof. Dr. Dr. h.c. Matthias H. Tschöp erhalten in diesem Jahr den mit jeweils 150.000 Euro dotierten Wissenschaftspreis der Weinheimer Hector Stiftung.

Stefanie Dehnen lehrt als Professorin für informationsbasiertes Materialdesign und Nanowissenschaften sowie für anorganische Chemie am Karlsruher Institut für Technologie (KIT). In ihrer Grundlagenforschung beschäftigt sie sich seit vielen Jahren mit chemischen Verbindungen. Als Expertin für innovative, anspruchsvolle und zugleich nachhaltige chemische Synthesen kombiniert sie aus den bekannten Elementen bisher unbekannte Verbindungen und Stoffe, die neue Eigenschaften haben. Diese sogenannten Clusterverbindungen gelten als das entscheidende Bindeglied zwischen einzelnen Atomen und nicht atomar definierten Nanopartikeln. Ihre ungewöhnlichen Eigenschaften und Reaktivitäten machen Clusterverbindungen zum Ausgangspunkt für innovative Funktionsmaterialien.

KIT

December 12, 2024

Scientists from Karlsruhe Institute of Technology (KIT) and the Indian Institute of Technology Guwahati (IITG) have developed a surface material that repels water droplets almost completely. Using an entirely innovative process, they changed metal-organic frameworks (MOFs) – artificially designed materials with novel properties – by grafting hydrocarbon chains. The resulting superhydrophobic (extremely water-repellent) properties are interesting for use as self-cleaning surfaces that need to be robust against environmental influences, such as on automobiles or in architecture. The study was published in the Materials Horizons journal. (DOI: 10.1039/D4MH00899E)

Xuchen Wang, KIT und Harbin Engineering University

November 11, 2024

Photonic space-time crystals are materials that could increase the performance and efficiency of wireless communication or laser technologies. They feature a periodic arrangement of special materials in three dimensions as well as in time, which enables precise control of the properties of light. Working with partners from Aalto University, the University of Eastern Finland and Harbin Engineering University in China, scientists from the Karlsruhe Institute of Technology (KIT) have shown how such four-dimensional materials can be used in practical applications. They published their results in Nature Photonics. (DOI: 10.1038/s41566-024-01563-3).

HealthTech@KIT

November 5, 2024

In future medicine, personalized computer models, so-called Virtual Human Twins, could help in the planning of individual therapies. Today already, human organs can be simulated on chips or in petri dishes: Scientists are developing computer-aided methods and in-vitro technologies that are intended to reduce or even replace animal testing. The new 3ROCKIT 3R Center at KIT (Karlsruhe Institute of Technology) is a driving force behind this endeavor. As of January 01, 2025, Baden-Württemberg will add it to the statewide 3R network, funding it with EUR 100,000 per annum for three years.

Amadeus Bramsiepe, KIT

November 5, 2024

The European Research Council (ERC) is funding the ATHENS research project headed by professors Christian Koos and Stefan Bräse of the Karlsruhe Institute of Technology (KIT) with a Synergy Grant. The project’s objective is to improve the performance and energy efficiency of optical communications systems. Given growing demand for the transmission of large volumes of data by artificial intelligence (AI) applications, such improvements are especially relevant. The ERC is funding ATHENS for six years with EUR 14 million. One location where work on the project will be performed is the Karlsruhe Center for Optics and Photonics (KCOP), which is set to open in 2025.

Irina Westermann, KIT

November 04, 2024

3,1 Millionen Euro für EU-Projekt NANO-S-MART: KIT forscht für besseres Produkt und weniger Verbrauch in der Stahlindustrie

Stahl gilt als „Musterschüler“ in der Recyclingindustrie und wird oft als vollständig wiederverwertbar angepriesen. Doch die Realität sieht anders aus: Jährlich exportiert Europa Stahlschrott in der Größenordnung des deutschen Stahlverbrauchs in Schwellenländer. „Die erforderlichen Materialqualitäten in Europa werden nicht mehr erreicht, weil sich durch den Kreislaufprozess Verunreinigungen im Stahl konzentrieren“, sagt Professor Christoph Kirchlechner vom Institut für Angewandte Materialien des KIT. „Unser Projekt will das Verständnis für den Umgang mit schädlichen Elementen im Recyclingprozess vertiefen und den Weg zu nachhaltigeren Materialkreisläufen ebnen.“

Jonathan Schneider, KIT

October 24, 2024

Metamaterials are artificial materials that do not occur in nature. Their components function like atoms in conventional materials but have special optical, electrical and magnetic properties. Interaction between the components is crucial to a metamaterial’s functionality. Previously a component could usually interact only with its immediate neighbors. Researchers at the Karlsruhe Institute of Technology (KIT) have developed a mechanical metamaterial with which these interactions can also be triggered at greater distances within the material. Potential uses of the material include measuring forces and structural monitoring. The findings have been published in Nature Communications. (DOI: 10.1038/s41467-024-52956-5).